Corynebacterium Diphtheriae Disease

Corynebacterium Diphtheriae Disease

Corynebacterium diphtheriae is a causative agent of diphtheria.It is upper respiratory tract illness and it is a contageous disease.

1. Morphology

  • It is a Gram positive, non-motile, non spore forming bacteria.
  • Corynebacteria is non- capsulated slender rod.
  • It shows club shaped swelling and hence called as Corynebacteria.
  • Its size ranges from 3-6 μm in lenght and 0.6-0.8 μm in width.
  • These cells posses metachromatic granules.
  • Mode of multiplication is by binary fission.

2. Cultural characters

  • Corynebacterium can grow easily on ordinary media.
  • It growth is enhanced by addition of blood or serum in the media.
  • It grows in a temperature range of 15° C-40° C and optimum temperature for its growth is 36° C.
  • Neutral pH is optimum for its growth.
  • Corynebacteria diphtheriae may be aerobic or facultative anaerobic in nature.
  • They are fast growing organism.

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Basics of Medical Microbiology

Basics of Medical Microbiology

Medical microbiology deals with studying the relationship between host and parasite and understanding the causative agent of disease.

In our daily life, human beings are constantly exposed to micro-organisms.
The interaction between human and micro-organisms may be useful or harmful interaction.
Parasitism can be explained a condition in which microbial population is benefited and the host is harmed.

Some important concepts in medical microbiology

1. Infection

  • In infection, a pathogen enters in a host body, lives and multiply in the host.
  • Generally, infection is caused due to the failure of host defence mechanism.
  • Due to the failure of host defence mechanism the microbial cells leads to infection.

2. Disease

  • The disease is a result of infection
  • When a disease is established the normal functioning of host body is disturbed and this disturbance results in signs and symptoms.
  • These pathogens not only multiply in the host but also releases some byproducts.
  • These byproducts may be toxic or non-toxic to host.

3.   Etiological agent

  • The etiological agent may be the causative agent of a disease
  • It may be an opportunistic pathogen

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